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Biopharma

Swiss Biotech Center offers capabilities of development and manufacturing of biopharmaceuticals on mammalian expression systems up to clinical batches under cGMP quality standards. We deliver bulks of low bioburden active pharmaceutical ingredients ready for formulation and  Fill&Finish.

Our state-of-the-art facility is operating with single-use technologies at each step of the process allowing an outstanding flexibility and rapidity, with a maximum batch size of 200L out of the bioreactor.

In addition to that, Swiss Biotech Center gathers a strong network of partners allowing to embark on a full development of biopharmaceuticals, from the DNA sequence of the target API to a sterile Fill&Finish of a Drug Product.

Technical characteristics

Environment

ISO 7 Cleanroom

Infrastructures

Single use

Production type

Volumes from 15L to 200L

- Cellular amplification -

- Upstream processing -

- Downstream processing -

- Downstream processing -

- In Process Control Room -

FILTER INTEGRITY TESTER

Fully automated tests

SINGLE-USE MULTIFUNCTIONAL SKID FOR DSP OPERATION

Ultrafiltration/diafiltration, viral inactivation, viral filtration and sterilisation

SINGLE-USE BIOREACTOR 200L

Work volume from 50L to 200L

SINGLE-USE BIOREACTOR 50L

Work volume from 12.5L to 50L

SINGLE-USE CHROMATOGRAPHY UNIT

Ready-to-process column from 1L to 20L

AUTOMATED CHEMICAL ANALYZERS

Quantification of nutrients, metabolites and gases in the culture

SCADA SUPERVISION SYSTEM

Bioprocess supervision, control and data acquisition

SINGLE-USE TANGENTIAL FILTRATION SYSTEM

Ultrafiltration, microfiltration, diafiltration
Recirculation volume of 10L
Filter area: 0.1-0.3m2